Robin Nusslock Assistant Professor

Program Area(s):

Brain, Behavior and Cognition; Clinical

Interest(s):

Mood and anxiety disorders; affective neuroscience

Research Interests

My research program examines the relationship between core-brain behavior dimensions and psychiatric symptoms of depression, bipolar disorder, and anxiety. Two dimensions that I am particularly focused on pertain to how the brain processes threatening and rewarding events in the environment. My colleagues and I propose that depression, bipolar disorder, and anxiety may be characterized by distinct profiles of reward processing and reward related brain function and that these profiles may reflect bio-signatures of differential risk. I take a multi-modal perspective to my research, incorporating neurophysiology (electroencephalography, event-related potentials) and both structural and functional neuroimaging.

Selected Publications

Nusslock, R., & Miller, G.E. (in press). Early-life adversity and physical and emotional health across the lifespan: A neuro-immune network hypothesis. Biological Psychiatry.

Young, C.B., & Nusslock, R. (in press). Positive mood enhances reward-related neural activity. Social, Cognitive, and Affective Neuroscience.

Pornpattananangkul, N., Hu, X., & Nusslock, R. (2015). Threat/reward-sensitivity and hypomanic personality modulate cognitive-control and attentional neural processes to emotional stimuli. Social, Cognitive, and Affective Neuroscience, 10, 1525-1536.

Pornpattananangkul, N., & Nusslock, R. (2015). Motivated to win: Relationship between anticipatory and outcome reward-related neural activity. Brain & Cognition, 100, 21-40.

Walden, K., Pornpattananangkul, N., Curlee, A., McAdams, D.P., & Nusslock, R. (2015). Posterior versus frontal theta activity indexes approach motivation during affective autobiographical memories. Cognitive, Affective, and Behavioral Neuroscience, 15, 132-144.

Alloy, L.B., Nusslock, R., & Boland, E.M. (2015). The development and course of bipolar spectrum disorders: An integrated reward and circadian rhythm dysregulation model. Annual Review of Clinical Psychology, 11, 213-250.

Salomons, T.V., Nusslock, R., Detloff, A., Johnstone, T., & Davidson, R.J. (2015). Neural emotion regulation circuitry underlying anxiolytics effects of perceived control over pain. Journal of Cognitive Neuroscience, 27, 222-233.

Nusslock, R., Young, C., & Damme, K. (2014). Elevated reward-related neural activation as a unique biological marker of bipolar disorder. Behaviour Research and Therapy, 62, 74-87.

Chase, H., Nusslock, R., Almeida, J.R.C., Forbes, E.E., LaBarbara, E.J., & Phillips, M.L. (2013). Dissociable patterns of abnormal frontal cortical activation during anticipation of an uncertain reward or loss in bipolar versus major depression. Bipolar Disorders, 15,839-854.

Nusslock, R., Harmon-Jones, E., Alloy, L.B., Urosevic, S., Goldstein, K.E, & Abramson, L.Y. (2012). Elevated left-frontal cortical activity prospectively predicts conversion to bipolar I disorder. Journal of Abnormal Psychology, 121, 592-601.

Nusslock, R., Almeida, J.R.C., Forbes, E.E., Versace, A., Frank, E., LaBarbara, E.J., Klein, C., & Phillips, M.L. (2012). Waiting to win: Elevated striatal and orbitofrontal cortical activity during reward anticipation in euthymic bipolar adults. Bipolar Disorders, 14, 249-260.

Alloy, L.B., Urosevic, S., Abramson, L.Y., Jager-Hyman, S., Nusslock, R., Whitehouse, W.G., & Hogan, M.E. (2012). Progression along the bipolar spectrum: A longitudinal study of predictors of conversion from bipolar spectrum conditions to bipolar I and II disorders. Journal of Abnormal Psychology, 121, 16-27.

Nusslock, R., & Frank, E. (2011). Subthreshold bipolarity: Diagnostic Issues and Challenges. Bipolar Disorders, 13, 587-603.

 Nusslock, R., Shackman, A.J., Coan, J.A., Harmon-Jones, E., Alloy, L.B., & Abramson, L.Y. (2011). Cognitive vulnerability and frontal brain asymmetry: Common predictors of first prospective depressive episode. Journal of Abnormal Psychology, 120, 497-503.